ESXi 6.5 introduces VMFS6, which supports both 512e and 512n devices.
What three configurations are supported when using these devices? (Choose three.)

A.
Hosts with both 512e and 512n devices.
B.
Storage vMotion between both 512e and 512n devices.
C.
Datastore Extents spanned between both 512e and 512n devices.
D.
Storage DRS clusters containing only both 512e and 512n devices.
Explanation:
VMFS can host both 512e and 512n devices. It also supports storage vMotion between 512e and 512n devices.
In addition to that DRS clusters can contain both 512e and 512n devices at the same time.
A,B,D
https://docs.vmware.com/en/VMware-vSphere/6.5/com.vmware.vsphere.storage.doc/GUID-7552DAD4-1809-4687-B46E-ED9BB42CE277.html
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When you work with VMFS5 and VMFS6 datastores, consider the following:
Upgrade – After you upgrade your ESXi hosts to version 6.5, you can continue using any existing VMFS5 datastores. To take advantage of VMFS6 features, create a VMFS6 datastore and migrate virtual machines from the VMFS5 datastore to VMFS6 datastore. You cannot upgrade the VMFS5 datastore to VMFS6.
Datastore Extents – A spanned VMFS datastore must use only homogeneous storage devices, either 512n or 512e. The spanned datastore cannot extend over devices of different formats.
Block Size – The block size on a VMFS datastore defines the maximum file size and the amount of space a file occupies. VMFS5 and VMFS6 datastores support the block size of 1 MB.
Storage vMotion – Storage vMotion supports migration across VMFS, vSAN, and Virtual Volumes datastores. vCenter Server performs compatibility checks to validate Storage vMotion across different types of datastores.
Storage DRS – VMFS5 and VMFS6 can coexist in the same datastore cluster. However, all datastores in the cluster must use homogeneous storage devices, either 512n or 512e. Do not mix devices of different formats within the same datastore cluster.
https://docs.vmware.com/en/VMware-vSphere/6.5/com.vmware.vsphere.storage.doc/GUID-7552DAD4-1809-4687-B46E-ED9BB42CE277.html
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“Datastore Extents. A spanned VMFS datastore must use only homogeneous storage devices, either 512n or 512e. The spanned datastore cannot extend over devices of different formats.”
“Storage DRS. VMFS5 and VMFS6 can coexist in the same datastore cluster. However, all datastores in the cluster must use homogeneous storage devices, either 512n or 512e. Do not mix devices of different formats within the same datastore cluster.”
https://docs.vmware.com/en/VMware-vSphere/6.5/com.vmware.vsphere.storage.doc/GUID-7552DAD4-1809-4687-B46E-ED9BB42CE277.html
Assuming D is a typo since it makes no sense anyway.
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D should be:
Storage DRS clusters containing only 512e or 512n devices.
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I agree, the wording is just wrong. A, B, D is what is being looked for as the correct answers.
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I can confirm that the actual exam was “Storage DRS clusters containing only 512e or 512n devices.”
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